After a decade of cold war, Scrooge McDuck reunites with his estranged nephew Donald Duck when he is asked to take care of his three nephews Huey, Dewey and Louie. The new arrivals rekindle Scrooge's sense of adventure, and he invites Donald and the boys to live at McDuck Manor with him, his housekeeper Mrs. Beakley and her granddaughter Webby Vanderquack. Together, they go on many new treasure hunting expeditions and globetrotting adventures while contending with villains like Flintheart Glomgold, the Beagle Boys, and Mark Beaks.