Vaughn (Jeffrey Dean Morgan) is essentially a kind man, but his youngest daughter's serious illness forces him to become a robber. Together with his partner Cox (Dave Bautista), the two designed to steal a huge sum of $3 million from the casino tycoon Pope (Robert DeNiro). However, this seemingly flawless plan fell apart at the last step. The person who was supposed to pick them up fled, causing Vaughn to hijack a bus and start his escape journey. In addition to the elderly and children on the bus, there is also a pregnant woman who is about to give birth. Driving this car, Vaughn not only has to avoid the tracking of SWAT Chris (Gina Carano) and her men, but also has to fight against the hunting of the killers sent by the Pope.